Figure 9From: Facilitation of the inhibitory transmission by gastrin-releasing peptide in the anterior cingulate cortex Activation of GRP receptors increased GABA release in IC neurons. (A and B) Bath application of GRP (300 nM) increased the frequency of sIPSCs in pyramidal neurons of IC (n = 11). (B) The effect of GRP was completely blocked by RC 3091 (3 μM) (n = 5). (C) However, no increase was observed in the presence of TTX (1 μM) (n = 5). (D) There is no effect of GRP on sEPSCs (n = 4). Holding potential for recording sEPSCs was -70 mV.Back to article page