Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity

Molecular Pain

Table 1 Incidence, onset latency and duration of muscle activities induced by chemical administration to the tooth pulp

	PBS		α,β-meATP (10 mM)		α,β-meATP (100 mM)		α,β-meATP (100 mM) + TNP-ATP (0.1 mM)		α,β-meATP (100 mM) + TNP-ATP (1 mM)
Muscle	Incidence	Latency (s)	Incidence	Latency (s)	Incidence	Latency (s)	Incidence	Latency (s)	Incidence	Latency (s)
GG	2/7	1.71 ± 0.46	2/4	2.13 ± 0.33	10/10	2.15 ± 0.53	4/4	3.56 ± 1.07	5/5	1.24 ± 0.46
AD	2/7	1.70 ± 0.45	2/4	1.80 ± 0.00	10/10	1.85 ± 0.46	2/4	3.76 ± 0.96	2/5	6.21 ± 2.42
MA	0/7	-	0/4	-	2/10	1.33 ± 0.00	0/4	-	0/5	-
		Duration (s)		Duration (s)		Duration (s)		Duration (s)		Duration (s)
GG	2/7	0.05 ± 0.00	2/4	1.87 ± 1.85	10/10	31.78 ± 8.04	4/4	2.30 ± 1.25 *	5/5	4.86 ± 2.10 *
AD	2/7	0.03 ± 0.02	2/4	0.03 ± 0.01	10/10	1.12 ± 0.52	2/4	0.02 ± 0.00	2/5	0.03 ± 0.01
MA	0/7	-	0/4	-	2/10	1.53 ± 0.19	0/4	-	0/5	-

GG, ipsilateral genioglossus muscle; AD, ipsilateral anterior digastric muscle; MA, ispilateral masseter muscle. Latency and duration were expressed as mean ± SEM. *: P < 0.05 (vs 100 mM α,β-meATP, Bonnferroni multiple t-test).

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