Skip to main content
Figure 3 | Molecular Pain

Figure 3

From: Prevention of Paclitaxel-induced allodynia by Minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats

Figure 3

Minocycline reduced up-regulation of ATF3 in DRG induced by paclitaxel. No ATF3-positive cells in L4 DRG were observed in the vehicle-treated rats (A). Following application of paclitaxel, there is a progressive and significant increase in the number of ATF3 positive cells in DRG (B-E), while in minocycline/paclitaxel-treated rats, ATF3 positive cells were significantly decreased (F, G). Histogram representing the mean number of ATF3 positive cells under various treated conditions (H). **P < 0.01 compared with the corresponding time points of paclitaxel group (n = 5/group).

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us