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Figure 5 | Molecular Pain

Figure 5

From: Prevention of Paclitaxel-induced allodynia by Minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats

Figure 5

Minocycline inhibited infiltration of macrophages into DRG induced by paclitaxel. There is a significant increase on days 4, 8 and 12 in the number of ED-1 positive cells in L4 DRG after paclitaxel treatment (B-E), *P < 0.05;**P < 0.01 compared with the vehicle group. ED-1 positive cells in minocycline/paclitaxel-treated rats were significantly decreased compared with the corresponding time points of paclitaxel group, ##P < 0.01 (F, G). Histogram represents the mean number of ED-1 positive cells under various treated conditions (H) (n = 5/group).

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Molecular Pain

ISSN: 1744-8069

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