Figure 5From: Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine Susceptibility of dorsal root, spinal nerve and sciatic nerve fibers to LPA-induced demyelination in the ex vivo culture model. Toluidine blue analysis was performed at 24 h after the addition of LPA (1 μM) to the ex vivo culture of dorsal root (DR), spinal nerve (SPN) or sciatic nerve (SCN) fibers. Results are calculated as a percentage of total fibers in each region, and expressed as the mean ± SEM from 3-5 independent experiments. *p < 0.05, vs. vehicle (Veh)-treated groups.Back to article page