Figure 4
From: Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons
Increased cAMP signal intensity in oxaliplatin treated neurons. A. Immunofluorescence images of cAMP positive adult rat DRG neurons acutely treated with 8-bromo-cAMP (positive control), or oxaliplatin for 15 minutes, compared to vehicle treated neurons. Bar = 50 μm. B. Fluorescence signal intensity for cAMP immunostaining (arbitrary units), was increased in oxaliplatin treated adult rat DRG neurons compared to positive controls, and significantly higher than vehicle treated neurons.