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Figure 1 | Molecular Pain

Figure 1

From: Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCϵ pathway in dorsal root ganglion neurons

Figure 1

Up-regulation of TRPV1 expression and enhancement of capsaicin-induced currents in DRG neurons of cancer rats. Compared with sham rats, TRPV1 expression was increased in ipsilateral DRGs at L4-6 of bone cancer rats (A and B). C: In the low current amplitude group, TRPV1 currents of DRG neurons in bone cancer rats were higher than that in sham-operated rats. D: In the high current amplitude group, a similar result as (C) was obtained. Inserted figures in (C and D) represent typical currents recorded in the low and high current groups, respectively.

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Molecular Pain

ISSN: 1744-8069

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