AGM Causes Pain-Related Behaviors via ASIC3 Channels. Pain-related behavior as determined by the time spent for paw licking following saline or AGM (1 mM) injection (10 μl) in the absence (white) or presence (grey) of hyperosmolarity (H-Osm, 600 mosmolkg-1 with mannitol), AA (10 μM), or lactate (15 mM, keeping the pH neutral). Data are means ± S.E.M. n = 6-9. *p < 0.05 versus saline; #
p < 0.05, asic3-/- versus asic3+/+; &
p < 0.05.