Table 1 Mean head withdrawal threshold values after saline or Complete Freund's Adjuvant (CFA) injection in the temporomandibular joint.
Stimulus | Time post injection | Ipsilateral (g) | Contralateral (g) | n° of rats | p value (ipsi vs. contra) | p value (ipsi vs. baseline) |
|---|---|---|---|---|---|---|
baseline | - | 15.5 ± 1.73 | 16.1 ± 2.06 | 12 | - | - |
saline | 4 h | 15.0 ± 0.00 | 20.5 ± 5.50 | 4 | 0.423 | 0.813 |
|  | 24 h | 12.7 ± 2.33 | 17.0 ± 4.73 | 4 | 0.457 | 0.395 |
|  | 48 h | 17.0 ± 4.73 | 17.0 ± 4.73 | 4 | 1.000 | 0.845 |
|  | 72 h | 16.3 ± 5.24 | 17.0 ± 4.73 | 4 | 0.929 | 0.962 |
CFA | 4 h | 10.1 ± 2.59 | 15.1 ± 3.07 | 8 | 0.231 | 0.088 |
|  | 24 h | 6.94 ± 1.45 | 14.0 ± 2.47 | 8 | < 0.05 | < 0.01 |
|  | 48 h | 5.33 ± 0.67 | 10.5 ± 0.96 | 8 | < 0.01 | < 0.01 |
|  | 72 h | 5.67 ± 1.20 | 12.7 ± 1.48 | 8 | < 0.01 | < 0.01 |