CPMs in P2Y
-/- mice have normal mechanical sensitivity. The response to 5, 10, 25, 50 and 100 mN mechanical stimuli is shown for CPM cells from WT and P2Y1-/- mice (A). Sharp electrode recordings from WT (grey) and P2Y1-/- (black) CPM cells revealed no significant difference between the strains in either the average mechanical threshold (B; mN), mean rate (C; spikes/sec; 5, 10, 25, 50 and 100 mN), or in the mean peak instantaneous frequency (D; Hz). Significance is indicated as p < 0.05 (*).