Figure 5
Oxaliplatin (OHP) treatment causes decreased the area of DRG cell body and nucleolus. Morphometric analysis revealed that DRG neurons from mice treated with oxaliplatin 3.5 mg/kg/iv twice weekly for four weeks (n = 3) had a significant decrease in the area (mm2) of the cell bodies (a) and nucleoli (c) compared to DRG neurons from naïve mice (n = 3). (b) There was no difference in the areas of the nuclei from oxaliplatin-treated and naïve mice. °p < 0.05 vs naïve, #p < 0.001 vs naïve, Student's T Test.