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Figure 4 | Molecular Pain

Figure 4

From: Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents

Figure 4

Activity of inflamed (CYP) bladder afferent fibers, normalized to the maximal activity of pre-drug stimulation. A) normalized activity before and after AZ12646915 alone (n = 29 fibers, 7 mice). B) normalized activity before and after AZ12646915 + AM251 (n = 19 fibers, 6 mice), C) normalized activity before and after AZ12646915 + AM630 (n = 19 fibers, 6 mice) and D) represents the percentage of the area under the curves from A, B and C. Data are mean ± SEM. Paired t-test was used for A, B and C and one sample t-test for D. * P < 0.05, **P < 0.01 and ***P < 0.001 versus pre-drug groups.

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Molecular Pain

ISSN: 1744-8069

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