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Table 1 Comparison of burst unit %, burst rate and % of nociceptive RT and VP neurons in Cav3.2 KO and WT mice under pentobarbital and urethane anesthesia

From: Involvement of the Cav3.2 T-type calcium channel in thalamic neuron discharge patterns

  Pentobarbital Urethane
  RT VP RT VP
Strain WT KO WT KO WT KO WT KO
Mouse N 9 9 9 9 8 8 8 8
% of burst 1 93.1 57.5 100 100 90 55 100 100
Unit N 17 19 29 47 8 7 9 8
% nociceptive unit 2 65 42 10 4 50 57 0 0
Spikes/s 3 8.6 ± 1.85 5.1 ± 2.4* 0.8 ± 0.1 1.2 ± 0.1 21.2 ± 3.3 15 ± 2.5 2.3 ± 0.3 1.6 ± 0.4
Bursts/s 4 0.53 ± 0.10 0.30 ± 0.06* 0.18 ± 0.03 0.27 ± 0.07* 1.42 ± 0.25 1.10 ± 0.17* 0.24 ± 0.09 0.40 ± 0.12
  1. 1, % of track with at least one typical RT or VP unit in tracks histologically identified
  2. 2, (nociceptive unit/total unit) × 100%
  3. 3, Average spike firing rate in 10 min recording period
  4. 4, Average burst rate in 10 min recording period
  5. 5, Mean ± SE
  6. *: P < 0.05 by t-test of WT and KO comparison