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Table 1 Comparison of burst unit %, burst rate and % of nociceptive RT and VP neurons in Cav3.2 KO and WT mice under pentobarbital and urethane anesthesia

From: Involvement of the Cav3.2 T-type calcium channel in thalamic neuron discharge patterns

 

Pentobarbital

Urethane

 

RT

VP

RT

VP

Strain

WT

KO

WT

KO

WT

KO

WT

KO

Mouse N

9

9

9

9

8

8

8

8

% of burst 1

93.1

57.5

100

100

90

55

100

100

Unit N

17

19

29

47

8

7

9

8

% nociceptive unit 2

65

42

10

4

50

57

0

0

Spikes/s 3

8.6 ± 1.85

5.1 ± 2.4*

0.8 ± 0.1

1.2 ± 0.1

21.2 ± 3.3

15 ± 2.5

2.3 ± 0.3

1.6 ± 0.4

Bursts/s 4

0.53 ± 0.10

0.30 ± 0.06*

0.18 ± 0.03

0.27 ± 0.07*

1.42 ± 0.25

1.10 ± 0.17*

0.24 ± 0.09

0.40 ± 0.12

  1. 1, % of track with at least one typical RT or VP unit in tracks histologically identified
  2. 2, (nociceptive unit/total unit) × 100%
  3. 3, Average spike firing rate in 10 min recording period
  4. 4, Average burst rate in 10 min recording period
  5. 5, Mean ± SE
  6. *: P < 0.05 by t-test of WT and KO comparison