Figure 6From: The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats "A" shows the release of glutamate and GABA in naïve, sham or SNI rats 7 days after injury. The values of extracellular GABA and glutamate in the mPFC were expressed as pmol in 10 μl of perfusate. * indicate significant difference vs sham rats. Each point represents the mean ± S.E.M of 7-8 animals per group. P values < 0.05 were considered statistically significant. "B" shows a panoramic picture of the pre-frontal cortex, the square indicates the pre/infra-limbic area. "C" shows a high magnification of the microdialysis probe location for aminoacid collection within the the pre/infra-limbic cortex. Coronal brain slices containing the sites of implantation of the microdialysis probes were obtained after the experiment and processed for histological analysis.Back to article page