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Figure 1 | Molecular Pain

Figure 1

From: Progesterone produces antinociceptive and neuroprotective effects in rats with microinjected lysophosphatidic acid in the trigeminal nerve root

Figure 1

Prolonged nociceptive behavior following the microinjection of LPA into the trigeminal nerve root of the rat. (A) Time course analysis of changes in the air-puff thresholds. LPA-treated animals showed significant decreased air-puff thresholds on postoperative day 3. LPA-induced mechanical allodynia was maintained until postoperative day 130. (B) Time course analysis of changes in the pin-prick responses. LPA injection produced significant mechanical hyper-responsiveness to pin-prick stimulation compared with the vehicle-treated group. (C) Time course analysis of changes in the thermal nociception. # P < 0.05, vehicle- vs. LPA-treated group. All points between two identical symbols have the same level of significance.

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Molecular Pain

ISSN: 1744-8069

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