Figure 3

mGluR5 KO mice have an increased intermicturition interval. A. Representative urodynamic profile of a WT mouse. B. Representative urodynamic profile of a mGluR5 KO mouse. A-C. The IMI in WT mice was significantly smaller when compared to mGluR5 KO mice (WT baseline IMI 212.3 ± 12.94 N = 3, mGluR5 KO IMI baseline 471.5 ± 29.14 N = 5). D. However, there was no difference in the bladder contraction amplitude. ***P < 0.001 unpaired Student's t-test compared to WT IMI.