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Figure 2 | Molecular Pain

Figure 2

From: Network dynamics in nociceptive pathways assessed by the neuronal avalanche model

Figure 2

Comparison of the neuronal avalanche of nociceptive responses in the ACC and S1 under light and deep anesthesia. (A) Colored lines indicate the distribution of avalanche size to probability in the ACC. The X-Y axis is on a log-log scale. The α values of the control condition (red) and pinch stimulation condition (light green) under light anesthesia are shown in the inset. (B) Neuronal avalanche size distribution in the S1. The α values in the control condition (red) and pinch stimulation condition (light green) under light anesthesia are shown in the inset. (C) The bar graph shows the significant change in the α value in the ACC during pinch stimulation under light anesthesia, and this effect was reversed under deep anesthesia. *p < 0.05, pinch stimulation vs. control under light anesthesia; # p < 0.05, pinch stimulation under light anesthesia vs. pinch stimulation under deep anesthesia. (D) The bar graph shows the significant change in the α value in the S1 during pinch stimulation under light anesthesia, and this effect was reversed under deep anesthesia. *p < 0.05, pinch or brush stimulation vs. control under light anesthesia; # p < 0.05, pinch or brush stimulation under light anesthesia vs. pinch or brush stimulation under deep anesthesia.

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