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Figure 3 | Molecular Pain

Figure 3

From: Lamina I NK1 expressing projection neurones are functional in early postnatal rats and contribute to the setting up of adult mechanical sensory thresholds

Figure 3

Neonatal substance P-saporin (SP-SAP) treatment selectively depletes NK1 + ve laminae I/III neurons at P48. A, B, C, Immunohistochemistry for NK1 in naïve rats (Figure 3A), rats treated with blank-saporin (blank-SAP) (Figure 3B) and rats treated with SP-SAP (Figure 3C) respectively. Scale bar, 50 μm. D, E, F, Immunohistochemistry for NeuN in naïve rats (Figure 3D), rats treated with blank-SAP (Figure 3E) and rats treated with SP-SAP (Figure 3F) respectively. Scale bar, 100 μm.

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