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Figure 2 | Molecular Pain

Figure 2

From: Milnacipran inhibits glutamatergic N-Methyl-D-Aspartate receptor activity in Spinal Dorsal Horn Neurons

Figure 2

(A) Milnacipran inhibits the response to exogenous NMDA. Milnacipran reversibly inhibited NMDA-induced currents. In this figure and subsequent figures, the horizontal bars above the chart recordings indicate the duration of drug superfusion. (B) The relative amplitudes were shown in the presence of milnacipran. ** P < 0.01, * P < 0.05 (C) Neither citalopram nor desipramine affected the amplitudes of NMDA-induced currents. (D) Comparison of the NMDA-induced currents in control and in the presence of citalopram or desipramine.

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