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Figure 2 | Molecular Pain

Figure 2

From: Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat

Figure 2

Evolution of the Knee-Bend score of animals injected with saline (control; n = 5) or 0.3, 1 or 2 mg of MIA (OA; n = 25/group) on various days after the injection until the day of sacrifice (3, 7, 14, 21, 31). At each sacrifice time-point 5 animals per group were euthanized. Baseline score was determined for all animals prior to the injection (day 0). * P < 0.05, ** P < 0.01, *** P < 0.001 significantly different from baseline values for the 0.3 mg dose of MIA; ## P < 0.01, ### P < 0.001 significantly different from baseline values for the 1 mg dose of MIA; § P < 0.05, §§ P < 0.01, §§§ P < 0.001 significantly different from baseline values for the 2 mg dose of MIA (Repeated Measures ANOVA followed by LSD post-hoc test).

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Molecular Pain

ISSN: 1744-8069

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