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Figure 3 | Molecular Pain

Figure 3

From: NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation

Figure 3

ZJ43 dose response in the PAG. Dose–response curves for ZJ43 injection into the PAG contralateral to the formalin injected site presenting the cumulative instances of formalin-evoked flinches during phase 1 and phase 2 of the formalin test (closed circles). Open circle represents sum of flinches by saline treated rats. ZJ43 or saline was microinjected into PAG 10 min before the formalin injection. Each point represents the mean of five to seven rats. ZJ43 reduced phase 1 and phase 2 flinching behavior 37.5 μg and 150 μg doses. * p < 0.05 as compared with the phase 1 or phase 2 responses in the saline treated rats (open circle).

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Molecular Pain

ISSN: 1744-8069

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