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Figure 7 | Molecular Pain

Figure 7

From: NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation

Figure 7

Dose–response curves for ZJ43 injection into the midline RVM presenting the cumulative instances of formalin evoked flinches during phase 1 and phase 2 of the formalin test. Drugs were administered into RVM 10 minutes before the formalin induction of inflammation. Each point represents the mean of responses of 5–7 rats. ZJ43 reduced phase 1 and phase 2 flinching behavior in a dose-dependent manner. **p < 0.01; ***p < 0.001 compared with the phase 1 or phase 2 responses in the saline treated rats.

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Molecular Pain

ISSN: 1744-8069

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