Figure 3
From: Gender, variation in opioid receptor genes and sensitivity to experimental pain
Association between OPRK SNPs and variability in muscle pressure pain thresholds (univariate analysis). a) Carriage of the OPRK rs7016778 A allele (genotype AA / AT, n=9, median 58.8 kPa (range 33.4-76.4)) had higher muscle pressure pain thresholds than non carriers (genotype TT, n=22, median 38.2 kPa (range 25.5-59.3)). p=0.008. b) Carriers of the OPRK rs7824175 C allele (genotype CC / CG, n=4, median 28.2 kPa (range 25.2-37.1)) had lower pain thresholds than non carriers (genotype GG, n=27, median 40.9 kPa (range 27.0-76.4)), p=0.01. Lines demonstrate median values.