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Figure 4 | Molecular Pain

Figure 4

From: Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine

Figure 4

Inhibition of the ASIC1a current by tetracaine. A, B and C. Representative current traces and summary data showing time-dependent decrease of ASIC1a current after rundown in the absence (n = 3, black) and presence (n = 4, red) of 3 mM tetracaine (Two-way ANOVA followed by Bonferroni posttests, ***p < 0.001). D, E and F. Representative current traces and summary data showing the frequency-dependent inhibition of the ASIC1a current in the absence (n = 5, black) and presence (n = 4, red) of 3 mM Tetracaine; (Two-way ANOVA followed by Bonferroni posttests, *p < 0.05; ***p < 0.001).

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