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Figure 7 | Molecular Pain

Figure 7

From: Subunit and frequency-dependent inhibition of Acid Sensing Ion Channels by local anesthetic tetracaine

Figure 7

Inhibition of voltage-gated Na+ current by acid. A. Representative current traces showing the inhibition of voltage-gated Na+ currents at pH 6.0 and 5.0 in DRG neurons. Neurons were held at -60 mV and stepped to potentials between −30 and −10 mV with 10 mV increments. B. Summary data showing that the peak Na+ currents at −30 mV were inhibited by acid (paired t test, n = 6; *p < 0.05, ***p < 0.001).

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Molecular Pain

ISSN: 1744-8069

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