Figure 2
From: Effect of amitriptyline on tetrodotoxin-resistant Nav1.9 currents in nociceptive trigeminal neurons
Effects of AMI on TTX-r Na v 1.9 currents, which were measured using whole-cell patch clamp recordings from TG neurons. A: The protocol of a single voltage step at −35 mV. B: Representative recordings of the Nav1.9 currents elicited by a single pulse before and after perfusion with 10 μM AMI. C: Concentration-dependent inhibition of AMI on Nav1.9 currents with the protocol in (A). Each point was normalized to the control (n = 6–9).