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Figure 1 | Molecular Pain

Figure 1

From: Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas

Figure 1

Nav1.8 and Nav1.9 expression in lingual neuromas. A and B. Nav1.8 and Nav1.9 immunolabelling was bright and appeared to be axon-specific, showing positive co-localisation with PGP9.5. Images showing immunofluorescent labelling in the lingual nerve neuromas for PGP9.5 (green) and Nav1.8 and Nav1.9 (red). The composite images show the expression of Nav1.8 and Nav1.9 within PGP9.5 labelled tissue (yellow). C. No positive staining for sodium channel subtypes was present where the primary antibodies were omitted. Images of lingual nerve neuromas following incubation with Nav1.8 antibody, Nav1.9 antibody, and secondary antibody alone (Control). Scale bar = 100 μm (A and C); 50 μm (B).

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Molecular Pain

ISSN: 1744-8069

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