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Figure 2 | Molecular Pain

Figure 2

From: Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas

Figure 2

Nav1.8 is expressed in human lingual nerve neuromas. A. Nav1.8 immunolabelling appeared greater in lingual nerve neuromas from patients with symptoms of dysaesthesia. Images of lingual nerve neuromas from patients without or with symptoms of dysaesthesia, showing double labelling with the general neuronal marker PGP9.5 (green) and Nav1.8 (red). Scale bar, 100 μm. B. The mean percentage area (± SEM) of PGP9.5 labelled tissue containing Nav1.8 was significantly higher in lingual nerve neuroma specimens taken from patients with symptoms of pain (unpaired t-test p = 0.0087; no pain 10.52 ± 4.93%, pain 31.82 ± 4.54%).

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Molecular Pain

ISSN: 1744-8069

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