Figure 7

TRPV1 is not functionally up-regulated in retrogradely labeled cutaneous neurons following skin-only incision injury. a. Percentage of cutaneous neurons responding to CAP. There is no difference in the percentage of labeled WT neurons responding to 500nM CAP from skin-only incised and sham mice. Neurons were pooled from 9 sham and 8 incised mice; three independent experiments were performed with no differences between experiments. b. Amplitude of responses of cutaneous neurons to CAP. The amplitude of responses to 500nM CAP for neurons from skin-only incised mice is not different than those from sham mice. Same neurons as in Figure 7a. c. Percentage of cutaneous neurons responding to CAP defined by IB4 staining. There is no difference in percentage of labeled neurons responding to 500nM CAP defined by IB4 binding. Same neurons as in Figure 7a. d. Amplitude of responses of cutaneous neurons responding to CAP defined by IB4 staining. The amplitude of responses to 500nM CAP for IB4-positive, labeled neurons from skin-only incised mice is not different than those from sham mice. Likewise, there is no difference in CAP responsiveness in IB4-negative neurons from incised and sham mice. Same neurons as in Figure 7a.