Skip to main content
Figure 5 | Molecular Pain

Figure 5

From: Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40

Figure 5

Effects of peripheral inflammation or spinal nerve injury on the GPR40 expression in the dorsal root ganglion (DRG) neurons. Double-staining for GPR40 (red) and NeuN (green) with DAPI (blue) indicated that GPR40 immunoreactivity mainly colocalized with a neuronal marker, NeuN in the DRGs even after the carrageenan, complete Freund’s adjuvant (CFA) or spinal nerve ligation (SNL) treatment. Lumbar DRGs (L4) were dissected 6 hours after carrageenan, 3 days after CFA, and 2–3 weeks after SNL treatment. As each control, saline, incomplete Freund’s adjuvant (IFA) and sham-treatment were employed, respectively. C-17 anti-GPR40 antibody was used. Scale bar = 50 μm.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us