Figure 3From: The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury Local inflammation induced by formalin injections is attenuated in BLT1KO mice. (A) Paw edema formation 1 h after formalin injection. (* p < 0.05 vs. BLT1WT mice, n = 5, unpaired Student’s t-test with Welch’s correction). (B) Quantification of Evans blue dye extravasation 1 h after formalin or vehicle injection. (p = 0.2366 vs. BLT1WT mice, n = 5-7, * p < 0.05 vs. vehicle, n = 5–7, Kruskal-Wallis with Dunn’s multiple comparison test). (C) Myeloperoxidase (MPO) activity in the paw 1 h after formalin injection. (* p < 0.05 vs. BLT1WT mice, n = 8–9, two-way ANOVA with a Bonferroni post hoc test).Back to article page