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Figure 3 | Molecular Pain

Figure 3

From: The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury

Figure 3

Local inflammation induced by formalin injections is attenuated in BLT1KO mice. (A) Paw edema formation 1 h after formalin injection. (* p < 0.05 vs. BLT1WT mice, n = 5, unpaired Student’s t-test with Welch’s correction). (B) Quantification of Evans blue dye extravasation 1 h after formalin or vehicle injection. (p = 0.2366 vs. BLT1WT mice, n = 5-7, * p < 0.05 vs. vehicle, n = 5–7, Kruskal-Wallis with Dunn’s multiple comparison test). (C) Myeloperoxidase (MPO) activity in the paw 1 h after formalin injection. (* p < 0.05 vs. BLT1WT mice, n = 8–9, two-way ANOVA with a Bonferroni post hoc test).

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