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Figure 2 | Molecular Pain

Figure 2

From: Anxiolytic-like effects of translocator protein (TSPO) ligand ZBD-2 in an animal model of chronic pain

Figure 2

Effects of ZBD-2 on pain perception. Mechanical allodynia and thermal hyperalgesia were detected on Day 0, 1, 7, 14 and 21 after CFA injection. ZBD-2 (0.15 and 1.5 mg/kg) did not change the mechanical allodynia in the ipsilateral (A) and contralateral hindpaw (B). ZBD-2 (0.15 and 1.5 mg/kg) did not change the thermal hyperalgesia in the ipsilateral (C) and contralateral hindpaw (D). (E) ZBD-2 did not reduce edema in CFA-injected hindpaws. n = 6 in each group, **p < 0.01 compared to the control group.

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Molecular Pain

ISSN: 1744-8069

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