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Figure 3 | Molecular Pain

Figure 3

From: In vivo patch-clamp analysis of the antinociceptive actions of TRPA1 activation in the spinal dorsal horn

Figure 3

Characterization of EPSCs induced by AITC. (A) Action of AITC (300 μM) on EPSCs in the presence of CNQX (40 μM). CNQX blocked EPSCs not only in the absence of AITC but also under its action. Traces of EPSCs are shown in an expanded scale in time, control (bottom left) and under the action of CNQX (bottom right). (B) A continuous chart recording of glutamatergic miniature EPSCs in the presence of TTX (0.5 μM) before and under the action of AITC (300 μM). (C) Summary of EPSC frequency (left) and amplitude (right) under the action of AITC (n = 5) relative to control.

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