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Fig. 5 | Molecular Pain

Fig. 5

From: Upregulation of T-type Ca2+ channels in long-term diabetes determines increased excitability of a specific type of capsaicin-insensitive DRG neurons

Fig. 5

Direct correlation between the AP parameters characterizing neuronal excitability and TCD in the caps−lpH+ DRG neurons. AP parameters were measured at the AP initiation threshold in Tyrode’s solution. TCD was measured in the same neurons at a voltage step from −100 to −50 mV when the external Tyrode’s solution was changed for TEA-Cl, Ba2+-based solution. a Significant correlation between the ADP/AHP area and TCD. Pearson coefficient Pc = 0.78, p < 1.2*10−5. Number of cells: n = 28 from eight rats b Significant correlation between the AP threshold and TCD. Pearson coefficient, Pc = 0.52, p < 0.0015. Number of cells: n = 36 from eight rats

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Molecular Pain

ISSN: 1744-8069

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