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Figure 3 | Molecular Pain

Figure 3

From: Spinal cord stimulation modulates supraspinal centers of the descending antinociceptive system in rats with unilateral spinal nerve injury

Figure 3

Double immunostaining of DβH and pCREB in representative bilateral LC tissues. ac Naïve rat, contralateral side; jl naïve rat, ipsilateral side; df SNL rat, contralateral side; mo SNL rat, ipsilateral side; gi SNL+SCS rat, contralateral side; pr SNL+SCS rat, ipsilateral side. s Quantitative summary of pCREB-positive neurons in bilateral LC regions. No significant difference in the number of pCREB-positive neurons was noted among the groups. t Quantitative summary of the ipsilateral-to-contralateral ratio of pCREB-positive neurons and DβH immunoreactivity in bilateral LC regions. Quantitative data were obtained from three consecutive slices of four animals per group. Data are mean ± SEM; *p < 0.05 and **p < 0.01 by the Tukey–Kramer test.

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