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Figure 1 | Molecular Pain

Figure 1

From: Distribution of raphespinal fibers in the mouse spinal cord

Figure 1

Termination pattern of BDA labeled fibers arising from RPa and ROb. ac An injection site in RPa and ROb, which involved the dorsal paragigantocellular reticular nucleus (red dashed circle). d A C8 section showing the labelled fibers in both the ventral and lateral funiculi (red arrows). e A C8 section showing labeled fibers in both the ventral and lateral funiculi (red arrows) and the medial lamina 7, and 8, and lamina 10. f A higher magnification of the rectangular area in e. Note labeled fibers in medial laminae 7, 8, and 9, and 10. g An L4 section showing labeled fibers in both the ventral and lateral funiculi (red arrows). Note there are more fibers in the lateral funiculus than in the ventral funiculus. h An L4 section showing labeled fibers in the lateral funiculus and in laminae 6–10. i A higher magnification of the rectangular area in h. j An S1 section showing labeled fibers in the lateral and ventral funiculi and in laminae 6–10. Note there are more fibers in the lateral funiculus than in the ventral funiculus. k A higher magnification of the rectangular area in j. l A T4 section showing labeled fibers in laminae 7–10 (red arrows). The scale bar 500 μm in ac, 400 μm in d and g, 200 μm in e, h, and j, 100 μm in f, i, k, l and the microphotograph in c.

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