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Fig. 1 | Molecular Pain

Fig. 1

From: Recruitment of dorsal midbrain catecholaminergic pathways in the recovery from nerve injury evoked disabilities

Fig. 1

Levels of dominance behaviour before and after nerve injury. Top panel mean durations (in seconds) of dominance behaviour (±SEM) measured: pre-injury (days 3–5); days 1–3 post-injury and; days 4–6 post-injury in behavioural controls, sham surgery rats and rats with Pain alone, Pain and Disability and Pain and Transient Disability. Significance with respect to pre-injury days is shown ***p < 0.001 (ANOVA, and post hoc Fischer’s PLSD). Lower panel individual data for Pain alone, Pain and Disability and Pain and Transient Disability post-CCI behavioural groups. Data are expressed as the mean percentage change from pre-CCI levels for days 1–3 post-CCI and days 4–6 post-CCI. The shaded area indicates a 30% reduction from pre-injury dominance behaviours. Rats that showed no differences in their post-CCI dominance behaviour were defined as Pain alone rats. Rats with a decrease of at least 30% in the duration of their dominance behaviours on 4 or more of the 6 days post injury days were defined as Pain and Disability rats. The rats that showed a 30% or more reduction in their dominance behaviours for days 1–3 post-CCI but then returned to pre-CCI levels were considered Pain and Transient Disability rats.

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