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Fig. 4 | Molecular Pain

Fig. 4

From: Amelioration of the reduced antinociceptive effect of morphine in the unpredictable chronic mild stress model mice by noradrenalin but not serotonin reuptake inhibitors

Fig. 4

Effects of escitalopram on the antinociceptive effect of morphine under the UCMS condition. The effects of escitalopram on the thermal pain sensitivity (a) and the antinociceptive effect of morphine (3 mg/kg; b) in a hot-plate test under the UCMS (white column vehicle, n = 11; gray column escitalopram 1 mg/kg, n = 12; black column escitalopram 3 mg/kg, n = 10) and non-stress (white column vehicle, n = 12; gray column escitalopram 1 mg/kg, n = 11; black column escitalopram 3 mg/kg, n = 9) conditions. Data are expressed as mean ± SEM.

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