Fig. 5
From: p38 phosphorylation in medullary microglia mediates ectopic orofacial inflammatory pain in rats
IL-1β protein in saline- or CFA-injected rats with i.c.m. vehicle or SB203580 administration. Photomicrographs of IL-1β-IR cells (a, d, g), Iba1-IR cells (b), IL-1β-IR and Iba1-IR cells (c), GFAP-IR cells (e), IL-1β-IR and GFAP-IR cells (f), NeuN-IR cells (h), and IL-1β-IR and NeuN-IR cells (i) in Vc on day 4 after CFA injection. The arrow indicates double-IR cells. j Relative amount of IL-1β protein in Vc on day 4 after CFA or saline injection with i.c.m. vehicle or SB203580 administration. β-Actin protein was used as loading control. Data represent mean ± SEM. n = 13 in each. *p < 0.05, **p < 0.01; by one-way ANOVA followed by Tukey’s multiple-comparison tests.