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Fig. 5 | Molecular Pain

Fig. 5

From: Pirt contributes to uterine contraction-induced pain in mice

Fig. 5

Dil-labeled DRG neurons respond to capsaicin. a Representative capsaicin-induced Ca2+ trace in DRG neuron from Pirt +/+ mouse. b Images of DRG neurons from Pirt +/+ mice before (B1) and after (B2) capsaicin treatment (5 μM). c Representative capsaicin-induced Ca2+ trace in DRG neuron from Pirt+/+ mouse. d Images of DRG neurons from Pirt−/− mice before (D1) and after (D2) capsaicin. Scale bar 20 µm. e The proportion of DRG neurons from Pirt +/+ and Pirt / mice that responded to capsaicin (% of total cells, *P < 0.05, n = 3/group). f 382 of 816 accounted Pirt +/+ positive cells were Dil-labeled cells (46 %). 120 of 382 Dil-labeled cells (31 %) responded to capsaicin. 204 of 816 Pirt +/+ neurons (25 %) responded to capsaicin

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