Figure 6

Sensory and locomotive function and growth of the mice. At 4 weeks and 12 weeks, none of the ssAAV9-shSOD1–injected mice showed any significant differences in body weight compared with controls (A). Similarly, in the von Frey test (B) and acetone test (C), none of the injected mice showed significant differences in sensory function compared with controls. In the accelerating rotarod test, all of the injected mice could perform the task similar to that of the controls (D). Each mouse was examined in 4 trials each day (T1–T4), for 4 consecutive days (D1–D4). There was no significant difference between the injected mice group and the control group. Data are presented as mean ± SEM (n = 7 for each group, P < 0.05).